Tuesday, November 27, 2012

MCQ in Microbiology: Immunology



  1. Naturally acquired active immunity would be most likely acquired through which of the following processes?
    a. vaccination
    b. Drinking colostrum
    c. Natural birth
    d. infection with disease causing organism followed by recovery.
  2. Which of the following convey the longest lasting immunity to an infectious agent?
    a. Naturally acquired passive immunity
    b. Artificially acquired passive immunity
    c. Naturally acquired active immunity
    d. All of these
    e. None of these
  3. Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?
    a. Antigen
    b. Virus
    c. Hapten
    d. Miligen
    e. Antibody


  4. B and T cells are produced by stem cells that are formed in:
    a. Bone marrow
    b. The liver
    c. The circulatory system
    d. The spleen
    e. The lymph nodes
  5. B cells mature in the........... while T cells mature in the
    a. Thymus/bone marrow and gut associated lymphoid tissue (GALT)
    b. Spleen/bone marrow and GALT
    c. Bone marrow and GALT/Thymus
    d. Liver/Kidneys
  6. Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?
    a. T helper cells
    b. B cells
    c. Antibodies
    d. Complement
    e. T cytolytic cells
  7. A living microbe with reduced virulence that is used for vaccination is considered:
    a. A toxoid
    b. Dormant
    c. Virulent
    d. Attenuated
    e. Denatured
  8. B cells that produce and release large amounts of antibody are called:
    a. Memory cells
    b. Basophils
    c. Plasma cells
    d. Killer cells
    e. Neutrophils
  9. The specificity of an antibody is due to
    a. its valence
    b. The heavy chains
    c. The Fc portion of the molecule
    d. The variable portion of the heavy and light chain
  10. In agglutination reactions, the antigen is a.........
    in precipitation reactions, the antigen is a...............
    a. whole cell/soluble molecule
    b. Soluble molecule/whole cell
    c. Bacterium/virus
    d. Protein/carbohydrates
    e. Protein/Antibody
  11. B Cells are activated by
    a. Complement
    b. Antibody
    c. Interferon
    d. Memory cells
    e. Antigen
  12. Fusion between a plasma cell and a tumor cell creates a
    a. Myeloma
    b. Natural killer cell
    c. Lymphoblast
    d. Lymphoma
    e. Hybridoma
  13. Monoclonal antibodies recognize a single:
    a. Antigen
    b. Bacterium
    c. Epitope
    d. B cell
    e. Virus
  14. Cell mediated immunity is carried out by.............. while humoral immunity is mainly carried out by....................
    a. B cells/T cells
    b. Epitopes/Antigens
    c. T cells/B cells
    d. Antibodies/Antigens
    e. Antibodies/Phagocytes
  15. The ability of the immune system to recognize self antigens versus nonself antigen is an example of:
    a. Specific immunity
    b. Tolerance
    c. Cell mediated immunity
    d. Antigenic immunity
    e. Humoral immunity   

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