MCQ in Microbiology: Immunology Questions and Answers with Explanation

This is the collection of some questions to check your understanding about immunology, main definitions, terms etc. At the end of this Immunology MCQ I have posted the answers also. I expect a person who have exposure to immunology must give correct answer at least for 14 questions, if you failed to do so, please revise immunology once again.

1. Naturally acquired active immunity would be most likely acquired through which of the following processes?
   a. vaccination
   b. Drinking colostrum
   c. Natural birth
   d. infection with disease causing organism followed by recovery.
   
    
2. Which of the following convey the longest lasting immunity to an infectious agent?
   a. Naturally acquired passive immunity
   b. Artificially acquired passive immunity
   c. Naturally acquired active immunity
   d. All of these
   e. None of these
   
   
3. Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?
   a. Antigen
   b. Virus
   c. Hapten
   d. Miligen
   e. Antibody
   
   
4. B and T cells are produced by stem cells that are formed in:
   a. Bone marrow
   b. The liver
   c. The circulatory system
   d. The spleen
   e. The lymph nodes
5. B cells mature in the........... while T cells mature in the
   a. Thymus/bone marrow and gut associated lymphoid tissue (GALT)
   b. Spleen/bone marrow and GALT
   c. Bone marrow and GALT/Thymus
   d. Liver/Kidneys
6. Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?
   a. T helper cells
   b. B cells
   c. Antibodies
   d. Complement
   e. T cytolytic cells
7. A living microbe with reduced virulence that is used for vaccination is considered:
   a. A toxoid
   b. Dormant
   c. Virulent
   d. Attenuated
   e. Denatured
8. B cells that produce and release large amounts of antibody are called:
   a. Memory cells
   b. Basophils
   c. Plasma cells
   d. Killer cells
   e. Neutrophils
9. The specificity of an antibody is due to
   a. its valence
   b. The heavy chains
   c. The Fc portion of the molecule
   d. The variable portion of the heavy and light chain
10. In agglutination reactions, the antigen is a.........
    in precipitation reactions, the antigen is a...............
    a. whole cell/soluble molecule
    b. Soluble molecule/whole cell
    c. Bacterium/virus
    d. Protein/carbohydrates
    e. Protein/Antibody
11. B Cells are activated by
    a. Complement
    b. Antibody
    c. Interferon
    d. Memory cells
    e. Antigen
12. Fusion between a plasma cell and a tumor cell creates a
    a. Myeloma
    b. Natural killer cell
    c. Lymphoblast
    d. Lymphoma
    e. Hybridoma
13. Monoclonal antibodies recognize a single:
    a. Antigen
    b. Bacterium
    c. Epitope
    d. B cell
    e. Virus
14. Cell mediated immunity is carried out by.............. while humoral immunity is mainly carried out by....................
    a. B cells/T cells
    b. Epitopes/Antigens
    c. T cells/B cells
    d. Antibodies/Antigens
    e. Antibodies/Phagocytes
15. The ability of the immune system to recognize self antigens versus nonself antigen is an example of:
    a. Specific immunity
    b. Tolerance
    c. Cell mediated immunity
    d. Antigenic immunity
    e. Humoral immunity
    
    Answers of MCQ Microbiology: Immunology
    

    1. 
       

       1. Ans: Its the easiest MCQ in microbiology. You have to know only the definition of naturally acquired active immunity. Naturally acquried active immunity is produced when the person is exposed to infectious agent. So the ans is d.
       2. Active immunity can last a lifetime or for a period of weeks, months or years, depending on how long the antibodies persist. So only one option in the choice contain active immunity as a part of answer. Ans is C
       3. Hapten is a small molecule, they can act as antigen if it binds to a larger protein molecule. So the ans is C
       4. This question asked you which stem cell is the immediate precursor of B Cell and T cell. The early development of stem cell takes place in primitive tissue, late development in fetal liver and final development in bone marrow. So the answer is bone marrow.
       5. Do you remember the term: T cells are thymus dervied cell? If you can remember, you already solved this question. If not you might rember differentiation of B Cell takes place in bone marrow and functional B cells are found in Gut associated Lymphoid tissue (GALT). Yes the right answer is C
       6. T cytolytic cell Tc cells and Natural killer cells kill infected host cells which are harboring intracellular pathogen. So ans is option E
       7. Attenuated means weakened. While making live attenuated vaccine the virulence of the microorganism is lost but its antigenic characterstics are retained. The ans is d.
       8. In this question: definition is given and the word is asked. The defintion of plasma cell is B Cell that is capable of producing large amount of antibodies.
          
          I have only posted the answers  of the questions from 9-15, if you have any problem to understand those, leave the comment.  I will try to help.
       9. The variable portion of heavy and light chain
       10. whole cell/soluble molecule
       11. Antigen
       12. Hybridoma
       13. Epitope
       14. T cells/B cells
       15. Tolerance