Monday, January 14, 2013

MCQ in Medical Microbiology: Immunology MCQs (11-20)


1.       Monoclonal antibodies are produced by
A)     hybridomas.
B)      lymphocytes.
C)      myeloma cells.         
D)     plasma cells.
       
2.       Opsonization refers to                  
A)     adherence to mucosal epithelial cells.
B)      antibody mediated viral inactivation.
C)      coating of microorganisms or other particles by antibody and/or complement.
D)     parasitic lysosomal degranulation.
3.       Which type of antibody is MOST effective in activating complement?
A)     IgG1
B)      IgG2
C)      IgG3
D)     IgM


4.       An anamnestic response involves a/an
A)     effector response. 
B)      high intensity.          
C)      rapid memory.
D)     All of the above.
               
5.       Cell-associated differentiation antigens (CDs) are functional cell surface proteins or receptors that can be measured in situ.
A)     Detecting these soluble molecules may help in the management of disease.              
B)      In normal individuals the concentration of these molecules in serum is always low.
C)      Thousands of CDs have been characterized.
D)     All of the above are true.

6.       The first tenet of clonal selection theory relies SPECIFICALLY on
A)     combinatorial joinings.
B)      somatic mutations.
C)      variations in the splicing process.
D)     B-cell clones.
7.       B-cells do which of the following?
A)     Act as antigen-processing cells
B)        Respond to antigens by making antibodies 
C)      Proliferate and differentiate into plasma cells
D)   All of the above

8.       Monoclonal antibodies are routinely used in all of the following EXCEPT
A)     the classification of leukemias.
B)      the identification and epidemiological study of infectious microorganisms.
C)      the identification of tumor antigens.
D)     the manipulation of the immune response.
9.       Which of the following DOES NOT play a role in antigen presentation?   
A)     MHC class I molecules
B)      MHC class II molecules
C)      MHC class III molecules
D)     None of the above

10.   Which of the following is used for typing when a patient is being prepared for an organ transplant?
A)     MHC class I molecules
B)      MHC class II molecules
C)      MHC class III molecules
D)     All of the above

Find the answers key of these MCQs in Immunology here: MCQ Immunology Answers Key

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