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MCQ in Medical Microbiology: Immunology MCQs(11-20)
MCQs in Immunology 21-30
MCQs in Immunology (Complement System) 31-40
MCQs in Immunology 21-30
MCQs in Immunology (Complement System) 31-40
MCQs (1-10)
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MCQs (11-20)
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MCQs (21-30)
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MCQs (31-40)
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1. A
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11. A
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21.C
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31. B
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2. B
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12. C
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22.E
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32. B
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3. D
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13. D
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23.D
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33. E
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4. C
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14. D
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24.B
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34. C
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5. A
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15. A
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25. C
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35.A
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6. A
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16. D
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26.C
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36.C
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7. C
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17. B
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27. A
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37. A
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8. C
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18. D
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28.A
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38 A
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9. A
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19. C
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29 D
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39 A
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10. B
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20. A
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30.D
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40 B and D
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Thanks I found your post interesting kindly assist me on the following.
ReplyDelete1 Ig idiotypes are found
In the constant region of the heavy chain
In the constant region of the light chain
In the variable region of both heavy and light chains
Only in the light chain
2 With reference to the variable Ig domain, which of these answers is false?
It mediates the secondary consequences of antigen recognition
It has anti-parallel beta-pleated sheet structures
It uses beta-turn loops to bind antigen
It has an extra long beta-turn relative to constant region domains
3 Which of the following statements does not apply to IgG
Appears early in the primary immune response
Neutralizes bacterial toxins
Can fix complement
Crosses the human placenta
4 IgA in seromucus secretions
Has no J-chain
Has no secretory piece
Is dimeric
Activates the classical complement pathway
5 IgM
Is usually of high affinity
Is most commonly tetrameric
Has the same number of constant domains as IgG
Is the main class of the 'natural antibodies'
6 IgD
Is resistant to proteolytic degradation
Is present mainly as a surface receptor on B-cells
Is present with unusual frequency in myelomas
Is abundant in milk
7 IgE
Binds strongly to mast cells
Cannot bind to macrophages
Activates the complement cascade
Has an insignificant role in worm infestations
8 The Fc receptor with the highest affinity of the following five receptors is
CD64
CD16
FceRI
CD23
9 Cleavage of IgG by papain produces
Divalent antigen binding fragments
Isolated light chains
Isolated heavy chains
Fab
10 A given myeloma protein
Has a homogeneous amino acid structure
Has diverse variable polypeptide segments
Has a constant heavy chain but both kappa and lambda light chains
Is produced by different plasma cell clones
11 What is the approximate number of D segment genes in the immunoglobulin heavy chain gene locus
40
30
9
6
12 A given Ig isotype is
A heavy chain variant encoded by allelic genes
A light chain constant region encoded by allelic genes
Present in all normal individuals
A collection of hypervariable region epitopes recognized by an anti-idiotype
13 The first immunoglobulin heavy chain class to be expressed on the surface of a newly produced B-cell is
IgA
IgD
IgE
IgM
14 A B-cell is able to make cell-surface and secreted versions of antibody using
Different gene pools
Differential splicing
Different heavy chain class but the same light chain
Different light chain class but the same heavy chain
15 The cytoplasmic region of surface IgM consists of
A single H chain constant region domain
A light chain
3 amino acids
Carbohydrate
16 The percentage of human peripheral blood T-cells bearing a gamma delta T-cell receptor is
100%
30–80%.
1-5%.
Only present during mycobacterial infections
17 The T-cell receptor genes were originally identified using
A monoclonal anti-idiotype
The polymerase chain reaction
A liver DNA gene lib
Subtractive hybridizationrary
18 A chromosome on which T-cell receptor alpha chain gene rearrangement has occurred lacks which of the following gene segments
Joining (J).
Diversity (D).
Variable (V).
TCR beta chain
19 N-region insertion is associated with the expression of
Terminal deoxynucleotidyl transferase
NK cell antigen receptors
The proteasome
Heat shock proteins
20 NK cells lack receptors with
Specificity for MHC class II molecules
Specificity for MHC class I molecules
C-type lectin domains
Immunoglobulin-like domains