Epidemiology,
Research Methods and Biostatistics
Title: Epidemiology, Research Methods and
Biostatistics Full marks: 50
Course No.: MB 515 Pass marks: 20
Nature of the course: Theory Year: I
Objectives
Upon the completion of the course students will have
knowledge on
- Scope and application of Epidemiology
- Research methods in Microbiology
- Application of Biostatistical methods in microbiological research.
Epidemiology
Overview of Epidemiology
Scope and applications of Epidemiology, Relation of
Epidemiology with Microbiology 2 hrs
Epidemiological Measurements
Health and disease, Indicators of Health and
Disease, Frequency Measures (Mortality, Morbidity, Incidence,
Prevalence, Incidence Density), Measures of Effect 4 hrs
Epidemiological Studies
Cross-sectional Study, Longitudinal Study, Descriptive Epidemiology,
Analytical Epidemiology, Experimental Epidemiology, Bias and Errors
in Epidemiological Studies:
Types and Sources of Error, Selection and
Information Bias, Confounding and Effect Modification, Screening:
Criteria of a screening test, selection and validity of a screening
test 10 hrs
Health Survey and
Surveillance
Types and design of survey, Disease Surveillance
systems 3 hrs
Outbreak Investigation
Concept of Epidemic, Endemic, Sporadic and Pandemic,
Investigation and Management of Disease Outbreaks 3
hrs
Infectious Disease
Epidemiology and Natural History of Disease
Sources
and
Reservoir
of
Infection,
Modes
of
Transmission,
Epidemiological
Markers
(phenotypic
and
genotypic
markers),
Interactions
of
agent,
host
and
environment,
Biological
Laws
of
Diseases,
Causation,
Prognosis,
Risk
Factors,
Establishing
the
Cause
of
a
Disease
6
hrs
Management of Diseases
Disease Prevention, Control, Elimination and
Eradication 2 hrs
Environmental and
Occupational Epidemiology
Environment and Health, Exposure and Dose,
Dose-effect and dose–response Relationship, Risk Assessment and
Risk Management 2 hrs
Research Methods
Research Methods
Introduction
and
objectives
of
Research,
Criteria
of
good
research
question,
Research
Process,
Priority
Areas,
Objectives/
Hypothesis
setting,
Literature
Review,
Critical
Appraisal
and
Meta
analysis,
Ethical
Issues
in
Research:
Salient
point
of
the
International
guidelines,
General
ethical
principles,
Informed
Consent
Scientific Writing: Paper
writing,
Proposal
writing,
Thesis/report
writing
(Seminar
presentations)
8
hrs
Biostatistics
Sampling, Data
Collection and
Frequency Distribution
Sample and Sampling, Sampling design and Sample
selection, Sample size and calculation, Qualitative and quantitative
data collection methods, Frequency Distribution 8
hrs
Data Analysis and Computer
Application
Quantitative data analysis (descriptive analysis,
inferential analysis- chi square, t-test, ANOVA, co-rrelation, 95%
CI, Standard error, Odds ratio, p-value, Regression analysis), Data
entry and Data analysis using computer software (SPSS, STATA, SAS,
Epi Info etc.) 12 hrs
Text books
1.
Detels R, McEwen J, Beaglehole R and Tanaka H, Oxford
Text Book of
Public Health,
4thEdition, Oxford University Press (2002).
2.
Park K. Park's Textbook
of Preventive
and Social
Medicine, 19th Edition, Banarsidas
Bhanot Publications, India (2007).
4. Gordis L.
Epidemiology, 3rd Edition, Elsevier Saunders
(2004).
5. Mahajan BK.
Biostatistics, Jaypee Brothers Medical
Publishers Pvt. Ltd, India
More Syllabus of M.Sc First Year Microbiology (Tribhuvan University)
More Syllabus of M.Sc First Year Microbiology (Tribhuvan University)
- Syllabus of M.Sc First year Immunology (TU)
- Syllabus of M.Sc First year Biochemistry-Instrumentation
- Syllabus of Microbial Biotechnology and Pharmaceutical Microbiology
- Syllabus of Microbial Structure, Physiology and Genetics
- Syllabus of Epidemiology, Research Methods and Biostatistics
- Syllabus of Practical Course on (MB 513+MB 514)
- Syllabus of Practical Course on (MB511+MB 512)
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