Sunday, March 4, 2012

Course Syllabus: TU M.Sc Microbiology First year:Epidemiology, Research Methods and Biostatistics


Epidemiology, Research Methods and Biostatistics

Title: Epidemiology, Research Methods and Biostatistics Full marks: 50
Course No.: MB 515 Pass marks: 20
Nature of the course: Theory Year: I

Objectives

Upon the completion of the course students will have knowledge on
  • Scope and application of Epidemiology
  • Research methods in Microbiology
  • Application of Biostatistical methods in microbiological research.

Epidemiology

Overview of Epidemiology
Scope and applications of Epidemiology, Relation of Epidemiology with Microbiology 2 hrs



Epidemiological Measurements
Health and disease, Indicators of Health and Disease, Frequency Measures (Mortality, Morbidity, Incidence, Prevalence, Incidence Density), Measures of Effect 4 hrs

Epidemiological Studies
Cross-sectional Study, Longitudinal Study, Descriptive Epidemiology, Analytical Epidemiology, Experimental Epidemiology, Bias and Errors in Epidemiological Studies:
Types and Sources of Error, Selection and Information Bias, Confounding and Effect Modification, Screening: Criteria of a screening test, selection and validity of a screening test 10 hrs
Health Survey and Surveillance
Types and design of survey, Disease Surveillance systems 3 hrs
Outbreak Investigation
Concept of Epidemic, Endemic, Sporadic and Pandemic, Investigation and Management of Disease Outbreaks 3 hrs
Infectious Disease Epidemiology and Natural History of Disease
Sources and Reservoir of Infection, Modes of Transmission, Epidemiological Markers (phenotypic and genotypic markers), Interactions of agent, host and environment, Biological Laws of Diseases, Causation, Prognosis, Risk Factors, Establishing the Cause of a Disease 6 hrs
Management of Diseases
Disease Prevention, Control, Elimination and Eradication 2 hrs
Environmental and Occupational Epidemiology
Environment and Health, Exposure and Dose, Dose-effect and dose–response Relationship, Risk Assessment and Risk Management 2 hrs

Research Methods

Research Methods

Introduction and objectives of Research, Criteria of good research question, Research Process, Priority Areas, Objectives/ Hypothesis setting, Literature Review, Critical Appraisal and Meta analysis, Ethical Issues in Research: Salient point of the International guidelines, General ethical principles, Informed Consent
Scientific Writing: Paper writing, Proposal writing, Thesis/report writing (Seminar presentations) 8 hrs

Biostatistics


Sampling, Data Collection and Frequency Distribution
Sample and Sampling, Sampling design and Sample selection, Sample size and calculation, Qualitative and quantitative data collection methods, Frequency Distribution 8 hrs


Data Analysis and Computer Application
Quantitative data analysis (descriptive analysis, inferential analysis- chi square, t-test, ANOVA, co-rrelation, 95% CI, Standard error, Odds ratio, p-value, Regression analysis), Data entry and Data analysis using computer software (SPSS, STATA, SAS, Epi Info etc.) 12 hrs

Text books


1. Detels R, McEwen J, Beaglehole R and Tanaka H, Oxford Text Book of Public Health, 4thEdition, Oxford University Press (2002).
2. Park K. Park's Textbook of Preventive and Social Medicine, 19th Edition, Banarsidas Bhanot Publications, India (2007).
4. Gordis L. Epidemiology, 3rd Edition, Elsevier Saunders (2004).

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